New evidence changes recommendations for aspirin in prevention of heart disease

The recommendations here have changed quite a bit. It's now all about risk.

For those between 50-59 years with a 10% or greater risk for cardiovascular disease, the evidence for taking aspirin is pretty good. For those between 60-69, the evidence is not solid and it's a good time for a chat with the doctor or advanced practitioner. For those under 50 or 70+, there isn't good evidence and again, time for a talk with the doc.

Not sure of your risk? That's a number you should know. It's much more important than LDL alone. Many calculators exist; here's one.